2015 Fiscal Year Final Research Report
Regulation of mesenchymal stem cell differentiation by the substrates immobilized with functional modules of extracellular matrix
| Project/Area Number |
26670456
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Endocrinology
|
|---|
| Research Institution | Yamagata University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
Hotta Junichi 山形大学, 大学院理工学研究科, 准教授 (80301919)
Furusawa Hiroyuki 山形大学, 大学院理工学研究科, 准教授 (60345395)
Kutsuzawa Koichi 東京工業大学, 大学院生命理工学研究科, 研究員 (90572066)
|
|---|
| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Keywords | 間葉系幹細胞 / バイオマテリアル / 再生医療 / Wntシグナル / 細胞増殖 |
|---|
| Outline of Final Research Achievements |
The proteins inducible of osteogenesis and adipogenesis are tried to immobilized to the substrate for the regulation of mesenchymal stem cell differentiation. Here, Wnt protein was successfully immobilized to the substrates to regulate cell growth and intracellular signaling.
|
| Free Research Field |
生体材料学
|
