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2014 Fiscal Year Final Research Report

Role of mitochondria in keratinaization

Research Project

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Project/Area Number 26670517
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Dermatology
Research InstitutionHokkaido University

Principal Investigator

ABE Riichiro  北海道大学, 医学(系)研究科(研究院), 准教授 (60344511)

Co-Investigator(Renkei-kenkyūsha) SUTO Asuka  北海道大学, 大学院医学研究科
Project Period (FY) 2014-04-01 – 2015-03-31
Keywordsミトコンドリア
Outline of Final Research Achievements

Mitochondria have many vital functions, including ATP production, calcium buffering and cell death. In keratinization, it is not well known the relationship of mitochondria and keratin. We investigated Mfn and showed mitochondria move along with keratin via Mfn in keratinocytes. In addition, abnormality of keratin induced defect of mitochondria function.

Free Research Field

皮膚免疫学

URL: 

Published: 2016-06-03  

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