2015 Fiscal Year Final Research Report
Identification of new chemical compound to induce pancreatic beta-cells
| Project/Area Number |
26670603
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Digestive surgery
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| Research Institution | Osaka University |
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Principal Investigator |
SAKAI Daisuke 大阪大学, 医学(系)研究科(研究院), 寄附講座助教 (10621071)
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| Co-Investigator(Kenkyū-buntansha) |
ISHII Hideshi 大阪大学, 大学院医学系研究科, 特任教授 (10280736)
KONNO Masamitsu 大阪大学, 大学院医学系研究科, 寄附講座助教 (80618207)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Keywords | 再生医学 / 糖尿病 / 発生・分化 |
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| Outline of Final Research Achievements |
We confirmed the differentiation efficiency to pancreatic beta-cell of chemical compounds using adipose derived mesenchymal stem cells. Identified chemical compounds were injected in ob/ob mouse and diabetes mellitus mouse. And we checked the blood glucose level of these mouse. It was showed that a few compounds were effective to treat the diabetes mellitus.
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| Free Research Field |
消化器外科学
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