2015 Fiscal Year Final Research Report
Identification of new chemical compound to induce pancreatic beta-cells
Project/Area Number |
26670603
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Multi-year Fund |
Research Field |
Digestive surgery
|
Research Institution | Osaka University |
Principal Investigator |
SAKAI Daisuke 大阪大学, 医学(系)研究科(研究院), 寄附講座助教 (10621071)
|
Co-Investigator(Kenkyū-buntansha) |
ISHII Hideshi 大阪大学, 大学院医学系研究科, 特任教授 (10280736)
KONNO Masamitsu 大阪大学, 大学院医学系研究科, 寄附講座助教 (80618207)
|
Project Period (FY) |
2014-04-01 – 2016-03-31
|
Keywords | 再生医学 / 糖尿病 / 発生・分化 |
Outline of Final Research Achievements |
We confirmed the differentiation efficiency to pancreatic beta-cell of chemical compounds using adipose derived mesenchymal stem cells. Identified chemical compounds were injected in ob/ob mouse and diabetes mellitus mouse. And we checked the blood glucose level of these mouse. It was showed that a few compounds were effective to treat the diabetes mellitus.
|
Free Research Field |
消化器外科学
|