2016 Fiscal Year Final Research Report
The possible role of IDH1 mutation, IGFBP7 and COLA1 for gliomagenesis.
Project/Area Number |
26670639
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Neurosurgery
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Research Institution | Gifu University |
Principal Investigator |
SOEDA Akio 岐阜大学, 医学部附属病院, 助教 (20444276)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Keywords | 悪性脳腫瘍 / IDH1変異 / IGFBP7 / COLA1 / 脳腫瘍幹細胞 |
Outline of Final Research Achievements |
The prognosis of malignant brain tumor depends on the presence or absence of IDH1 mutation. It is also known that malignant brain tumors contain cancer stem cells that are the source of tumors. We have showed that IGFBP 7 and COLA 1 are involved in malignant tumor diversity.
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Free Research Field |
脳神経外科学分野
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