In vitro bone generation trial using multi-walled carbon nanotube blocks

2015 Fiscal Year Final Research Report

• Project/Area Number: 26670658
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Orthopaedic surgery
• Research Institution: Shinshu University
• Principal Investigator: TANAKA Manabu 信州大学, 医学部附属病院, 医員 (30723069)
• Co-Investigator(Kenkyū-buntansha): SATO Yoshinori 東北大学, 環境科学研究科, 准教授 (30374995) ; HANIU Hisao 信州大学, 学術研究院医学系, 准教授 (30252050)
• Co-Investigator(Renkei-kenkyūsha): SAITO Naoto 信州大学, 学術研究院保健学系, 教授 (80283258) ; AOKI Kaoru 信州大学, 医学部, 准教授 (30467170)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Keywords: カーボンナノチューブ / 再生医療 / 整形外科

Outline of Final Research Achievements

Multi-walled carbon nanotubes were formed in a shape suitable for bone regeneration (CNTp), and evaluated the possibility of applications in bone regeneration medicine. We couldn't produce bones in vitro but CNTp showed good cell proliferation, bone conduction, and excellent capacity to hold and release of the drug sustainably. It was suggested that CNTp can be applied to regenerative medicine using tissue engineering not only as a filler of the bone defect, but also as a scaffold material transplanted by culturing cells and as a carrier for controlled release of drugs.

Free Research Field

整形外科