Determination of the range of resection in conization of the cervix with chemical navigation of novel fluorescent probe

2015 Fiscal Year Final Research Report

• Project/Area Number: 26670727
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Obstetrics and gynecology
• Research Institution: Nara Medical University
• Principal Investigator: Iwai Kana 奈良県立医科大学, 医学部, 助教 (60588531)
• Co-Investigator(Kenkyū-buntansha): KANAYAMA SEIJI 近畿大学, 医学部附属病院, 講師 (10423914) ; TANASE YASUHITO 奈良県立医科大学, 医学部, 助教 (20423915) ; HURUKAWA NAOTO 奈良県立医科大学, 医学部, 研究員 (50347556) ; KAWAGUCHI RYUJI 奈良県立医科大学, 医学部, 講師 (50382289)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Keywords: 子宮頸癌 / GGT / 円錐切除術 / 前癌病変

Outline of Final Research Achievements

The aim of this research is the clinical application of surgical navigation system for determination of the range of resection in conization. We revealed that the staining intensity in the immunohistochemistry for GGT in microinvasive cancer was strong. But there was no significant difference between CIN1 and microinvasive cancer. We could revealed the possibility that GGT expressed increasingly in microinvasive canser. We want to realize chemical navigation system with novel fluorescent probe in conization.

Free Research Field

婦人科腫瘍