2015 Fiscal Year Final Research Report
The feasibility of regenerative treatment for alveolar cleft with umbilical cord blood-derived mesenchymal stem cells.
Project/Area Number |
26670779
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Plastic surgery
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Research Institution | Tokai University |
Principal Investigator |
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Project Period (FY) |
2014-04-01 – 2016-03-31
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Keywords | 唇顎口蓋裂 / 出生前診断 / 臍帯血 / 間葉系幹細胞 |
Outline of Final Research Achievements |
The objective of this research was to evaluate the feasibility of regenerative treatment for alveolar cleft with umbilical cord blood-derived mesenchymal stem cells. Recent progress of ultrasound examination has brought prenatal diagnosis of cleft lip and palate, and also brought the opportunity for the umbilical cord blood harvest of the patient. We examined the possibility for osteoblast differentiation of mesenchymal stem cells from cryopreserved human umbilical cord blood and in-vivo osteogenesis in severe immunodeficiency rat.
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Free Research Field |
唇顎口蓋裂
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