Elucidation of the oral biofilm prevention mechanism by photocatalytic devices and their practical application

2016 Fiscal Year Final Research Report

• Project/Area Number: 26670901
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Social dentistry
• Research Institution: University of Tsukuba
• Principal Investigator: YANG Yingnan 筑波大学, 生命環境系, 教授 (50561007)
• Co-Investigator(Renkei-kenkyūsha): KAWAZOE Naoki 国立研究開発法人物質・材料研究機構, 機能性材料研究拠点, 主幹研究員 (90314848)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 光触媒デバイス / バイオフィルム / 口腔衛生 / 反応機構

Outline of Final Research Achievements

In order to prevent the oral biofilm, a developed photocatalytic device used for detect the practical effect and the prevention mechanism also be elucidated.
P/Ag2O/Ag/Ag3PO4/TiO2, a novel photocatalyst developed in our lab was used in this research. In this research, the optimal molecular weight and addition dosage of PEG and calcination temperature, time and number of coating layers was investigated to optimize the coating condition of PEGm-P/Ag/Ag2O/Ag3PO4/TiO2 photocatalytic thin film. The result of E.coli (107CFU/ml) inactivation by using PEG modified photocatalyst showed that all of the E.coli was destroyed by P/Ag/Ag2O/Ag3PO4/TiO2 only in 10 minutes, but pure TiO2 have little effect on sterilization. Furthermore, the oral biofilm prevention effect have been demonstrated and the mechanism also be elucidated. The valuable information for future practical application have been obtained.

Free Research Field

生物工学