Creation of Highly Sensitive SERS Particles for Visualization of Chemical Reactions in Cells

2017 Fiscal Year Final Research Report

• Project/Area Number: 26708025
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Partial Multi-year Fund
• Research Field: Polymer/Textile materials
• Research Institution: Tohoku University
• Principal Investigator: YABU HIROSHI 東北大学, 材料科学高等研究所, 准教授 (40396255)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 自己組織化 / 微粒子 / 有機-無機ハイブリッド / ラマン散乱 / 細胞

Outline of Final Research Achievements

By using the original self-organized precipitation (SORP) method, core-shell particles comprising of polystyrene core and amino-terminated polybutadiene shell have been prepared. Since obtained particles have positive surface charges, composite particles having gold nanoparticle clusters were successfully prepared by mixing negatively charged gold nanoparticle dispersions with core-shell particles. These particles show strong surface enhanced Raman scattering signals by irradiation of near infrared light excitation. Furthermore, magnetic responsive composite particles were also prepared by introducing magnetic nanoparticles into the composite particles.

Free Research Field

高分子化学