2017 Fiscal Year Final Research Report
Three-dimensional cell assembly and muscle tissue formation for biohybrid robotic system
| Project/Area Number |
26709013
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Partial Multi-year Fund |
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| Research Field |
Intelligent mechanics/Mechanical systems
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| Research Institution | Shinshu University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Keywords | バイオハイブリッド / 組織工学 / バイオMEMS / 磁気アルキメデス効果 |
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| Outline of Final Research Achievements |
Bio-hybrid devices are based on the integration of living biological objects and artificial mechanical structures. We aim to construct a muscle tissue directly on a microstructure to realize a biohybrid device that utilizes muscle tissue as its actuator. In this study, we assembled rat cardiomyocytes around two micropillars three-dimensionally by magnetic levitation based on the magneto-Archimedes effect. Finally, we confirmed that the constructed myocardial tissues contracted in response to the electrical stimulation and the contractions deformed the micropillars.
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| Free Research Field |
ナノマイクロシステム
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