2017 Fiscal Year Final Research Report
Studies on entry and nuclear egress of Herpes Simplex Virus
| Project/Area Number |
26713017
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Partial Multi-year Fund |
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| Research Field |
Virology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
Arii Jun 東京大学, 医科学研究所, 助教 (30704928)
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| Research Collaborator |
KAWAGUCHI Yasushi 東京大学, 医科学研究所, 教授
KATO Akihisa 東京大学, 医科学研究所, 助教
KOYANAGI Naoto 東京大学, 医科学研究所, 特任研究員
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Keywords | HSV / 糖タンパク質 / 膜タンパク質 / 核膜 / 細胞膜 |
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| Outline of Final Research Achievements |
We investigated the mechanism by which HSV passes though cellular membranes. We successfully identified several viral or cellular factors which promote passage through cellular membranes of HSV. As these steps are essential for viral life cycle, our results may indicate new prophylactic and therapeutic approaches for the development of antiherpetic drugs.
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| Free Research Field |
ウイルス学
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