Uterus transplantation research with cynomolgus monkeys and survey of attitudes toward uterus translpantion

2015 Fiscal Year Final Research Report

• Project/Area Number: 26713050
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Partial Multi-year Fund
• Research Field: Obstetrics and gynecology
• Research Institution: Keio University
• Principal Investigator: Kisu Iori 慶應義塾大学, 医学部, 特任助教 (30445267)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Keywords: 生殖医学

Outline of Final Research Achievements

We performed uterus allo-transplantaion with cynomolgus monkeys. Establishments of surgical procedure, protocol of immunosupressants and rejection diagnosis were examined in this study. The allowable warm ischemic time was examined and it was figured out that four hours was acceptable in cynomolgus monkeys, but the uterus which kept ischmemia for 8 hours was atrophied.
Moreover, surveys of attitudes toward uterus transplantaion was performed with internet web-site. Our results suggest that many Japanese women of reproductive age feel that UTx is socially and individually acceptable, but that concerns requiring further discussion remain among these women. There was also a tendency for UTx to be viewed more favorably than gestational surrogacy.

Free Research Field

婦人科腫瘍