2016 Fiscal Year Final Research Report
A Flexible Protein Structure Alignment Method Based on the Residue-Residue network comparison
| Project/Area Number |
26730151
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Life / Health / Medical informatics
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| Research Institution | Kitasato University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | タンパク質立体構造 / 立体構造アライメント / 構造比較 / タンパク質三次元構造 |
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| Outline of Final Research Achievements |
In this project, we developed a new protein structure alignment method, contact area-based alignment (CAB-align), which uses the residue-residue contact area to identify regions of similarity. Our novel algorithm can identify homologous relationships at the residue level between related protein structures.
The software is freely available to academic users as stand-alone software at http://www.pharm.kitasato-u.ac.jp/bmd/bmd/Publications.html.
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| Free Research Field |
バイオインフォマティクス
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