2016 Fiscal Year Final Research Report
Effects of dietary glycerophospholipids on immune systems
| Project/Area Number |
26750044
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Eating habits
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| Research Institution | University of the Ryukyus |
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Principal Investigator |
INAFUKU Masashi 琉球大学, 熱帯生物圏研究センター, 協力研究員 (90457458)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Keywords | グリセロリン脂質 / 食事 / 免疫 |
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| Outline of Final Research Achievements |
Dietary glycerophospholipids affected on the increase in serum inflammatory cytokine levels of mice treated with immunostimulants.Dietary phosphatidylcholine or phosphatidylinositol inhibted these increases, whereas phosphatidylserine enhanced. Among the inflammatory cytokines, interferon-gamma levels were significantly affected by dietay phospholipids.Dietary phosphatidylinositol significantly increased the number of splenic T lymphocytes, but decreased that interferon-gamma producing T-cells. In splenic T lymphocytes of mice fed phosphoatidylinositol, significant alleviation of interferon-gamma producing ability were shown when extracellular but not intracellular activation.
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| Free Research Field |
脂質応用学、食品機能学
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