2016 Fiscal Year Final Research Report
Search of foods inhibiting lipoxygenase for prevention of allergic disease
| Project/Area Number |
26750049
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Eating habits
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| Research Institution | Okayama Prefectural University |
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Principal Investigator |
Kawakami Yuki 岡山県立大学, 保健福祉学部, 准教授 (30453202)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | リポキシゲナーゼ / 食品 / 抗アレルギー作用 |
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| Outline of Final Research Achievements |
5-Lipoxygenase is an enzyme that catalyzes formation of leukotrienes. Leukotrienes are implicated in inflammatory processes and allergic reaction such as asthma. We evaluated the inhibitory effect of various foods on 5-lipoxygenase activity. We found that nutmeg contained a potent inhibitor of 5-lipoxygenase. We identified an inhibitor of 5-lipoxygenase in nutmeg and established an efficient extraction protocol.
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| Free Research Field |
食品生化学
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