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2016 Fiscal Year Final Research Report

Fabrication of paste-like artificial bones with enhanced biological properties

Research Project

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Project/Area Number 26750159
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Biomedical engineering/Biomaterial science and engineering
Research InstitutionOkayama University

Principal Investigator

Konishi Toshiisa  岡山大学, 自然科学研究科, 助教 (10587843)

Co-Investigator(Renkei-kenkyūsha) Hayakawa Satoshi  岡山大学, 大学院自然科学研究科, 教授 (20263618)
Yoshioka Tomohiko  岡山大学, 大学院自然科学研究科, 準教授 (50452016)
Research Collaborator Nagano Yasuyuki  
Project Period (FY) 2014-04-01 – 2017-03-31
Keywordsリン酸カルシウム / 銅 / 骨補填材 / 骨伝導 / 血管新生
Outline of Final Research Achievements

With the intent to combine osteoconductivity with angiogenic property, the present study aimed to fabricate copper and silicon co-doped β-tricalcium phosphates (β-TCP).
Copper-doped β-TCP(s) were successfully synthesized via both solid-state and liquid-phase reaction. In addition, the effect of copper on the dissolution behaviors of copper TCP (CuTCP) was also investigated. The incorporation of copper in the β-TCP resulted in a decrease in the dissolution rate of CuTCP, which was caused by a rate-determining dissolution process of a disordered phase around the CuTCP.

Free Research Field

バイオマテリアル

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Published: 2018-03-22  

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