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2016 Fiscal Year Final Research Report

Molecular biological analysis of rehabilitation on osteoarthritis

Research Project

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Project/Area Number 26750185
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Rehabilitation science/Welfare engineering
Research InstitutionOkayama University

Principal Investigator

Kumagishi Kanae  岡山大学, 医学部, 客員研究員 (10597892)

Co-Investigator(Renkei-kenkyūsha) HIROHATA Satoshi  岡山大学, 保健学研究科, 教授 (90332791)
OHTSUKI Takashi  岡山大学, 保健学研究科, 非常勤研究員 (10534802)
SHINAOKA Akira  岡山大学, 医歯薬学総合研究科, 助教 (90724500)
Kawamura Kenji  吉備国際大学, 保健福祉学部, 教授 (40278974)
Research Collaborator SAKAI Takahumi  
Project Period (FY) 2014-04-01 – 2017-03-31
Keywords変形性膝関節症 / リハビリテーション / 軟骨破壊 / 運動療法 / ヒアルロン酸
Outline of Final Research Achievements

The purpose of this study was to analyze the effect of intra-articular injection of hyaluronan(HA) under mechanical stimulation (MS) in joints of osteoarthritis. We used physiological and biochemical methods.
Our results show that therapy HA injections with mechanical stimulation in OA decriced MMP13 and Cytokines and histologically significant improvement of articular degradation compared with only MS.

Free Research Field

変形性膝関節症

URL: 

Published: 2018-03-22  

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