2016 Fiscal Year Final Research Report
Repeater F-waves in patients with poliomyelitis
Project/Area Number |
26750211
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Rehabilitation science/Welfare engineering
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Research Institution | University of Occupational and Environmental Health, Japan |
Principal Investigator |
|
Research Collaborator |
KOMORI Tetsuo
ABE Tatsuya
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Keywords | F波 / 反復F波 / ポリオ後症候群 / 運動ニューロン疾患 / 前角細胞障害 / 波形解析 / 末梢神経障害 |
Outline of Final Research Achievements |
The purpose of this study was to determine whether F-waves reveal electrophysiological features of anterior horn cells in polio survivors. Forty-three polio survivors and 20 healthy controls underwent motor nerve conduction studies of the median and tibial nerves bilaterally, including F-waves and the determination of motor unit number estimate(MUNE). A significant increase in repeater F-waves and a reduction of F-wave persistence were observed in both nerves in the polio group as compared with the control group. Repeater F-waves had a negative correlation with MUNE. Furthermore, as polio severity worsened, repeater F-waves increased, followed by a reduction in F-wave persistence. These findings suggest that repeater F-waves are an early sign of motor unit pathology in polio survivors.
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Free Research Field |
リハビリテーション医学
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