2015 Fiscal Year Annual Research Report
Selective C-H Bond Transformations via Single-Electron Transfer Processes
| Project/Area Number |
26810017
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| Research Institution | The University of Tokyo |
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Principal Investigator |
ユー ウージン 東京大学, 理学(系)研究科(研究院), 助教 (70626077)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Keywords | copper catalysis / photocatalysis / C-N bond formation / cross-coupling reaction / visible light |
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| Outline of Annual Research Achievements |
During the funding period, we have been investigating the productive merger between visible photoredox catalysis and copper catalysis to mediate challenging C-N bond formation processes. We have demonstrated that the cross-coupling reaction between arylboronic acids and aniline derivatives could be performed under mild reaction conditions with broad substrate scope by introducing a photocatalyst under visible light irradiation in air. We have also found that by using a similar catalytic system, we could efficiently form C-N bonds between carbazoles with aryl iodides. However, it was found that this particular transformation was limited only to carbazoles, and the use of other types of amine-based nucleophiles led to poor results.
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