2016 Fiscal Year Final Research Report
Modular Synthesis of Arylalkanes Using Organosulfur Compounds
Project/Area Number |
26810056
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Synthetic chemistry
|
Research Institution | Nagoya University |
Principal Investigator |
Nambo Masakazu 名古屋大学, トランスフォーマティブ生命分子研究所, 特任助教 (10705528)
|
Research Collaborator |
CRUDDEN Cathleen M. クイーンズ大学, 教授
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Keywords | アリールアルカン / 炭素-スルホニル結合活性化 / 有機硫黄化合物 / パラジウム触媒 / 逐次的自在合成 / C-H官能基化 / 有機ホウ素化合物 |
Outline of Final Research Achievements |
We have developed methyl sulfone derivatives as new reacting templates in Pd-catalyzed sequential arylations directed toward the modular synthesis of multiply-arylated methanes. This method enabled the rapid synthesis of thyroid hormone receptor b-selective analog (GC-24) and the development of new inhibitor for plant cell division.
|
Free Research Field |
有機合成化学
|