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2016 Fiscal Year Final Research Report

Functional molecular robot using RNA/RNP nanostructures

Research Project

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Project/Area Number 26810089
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Bio-related chemistry
Research InstitutionOsaka University (2015-2016)
Kyoto University (2014)

Principal Investigator

Shibata Tomonori  大阪大学, 産業科学研究所, 特任助教(常勤) (80711960)

Project Period (FY) 2014-04-01 – 2017-03-31
KeywordsRNA / タンパク質 / 核酸ナノテクノロジー
Outline of Final Research Achievements

We designed and constructed RNA-protein complex-based functional molecular robots that exert desired funtions in response to proteins. The functional molecular robots consisting of RNA and protein can be constructed within live cells. We demonstrated that mammalian cell fate can be controlled using functional molecular robots. Construction of a molecular robot that functions in a particular cell will be useful for medical applications.

Free Research Field

ケミカルバイオロジー

URL: 

Published: 2018-03-22  

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