2015 Fiscal Year Final Research Report
Analysis of intron-retaining form of DNA repair-related mRNAs
| Project/Area Number |
26840008
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Molecular biology
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| Research Institution | Hokkaido University (2015)
Kyoto University (2014) |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Keywords | スプライシング / ストレス応答 |
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| Outline of Final Research Achievements |
Signal-induced splicing of nuclear intron-retaining RNA is a novel regulation mechanism of gene expression. However, it was still unclear what kinds of genes are controlled in a similar manner. Next generation sequencing and bioinformatics analyses revealed that some of promising candidates for novel intron-retaining RNAs are related to DNA damage response and regulated by DNA damage agents.
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| Free Research Field |
分子生物学
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