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2016 Fiscal Year Final Research Report

Bioelectrical signal controls skin pattern formation of zebrafish

Research Project

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Project/Area Number 26840080
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Developmental biology
Research InstitutionOsaka University

Principal Investigator

ARAMAKI Toshihiro  大阪大学, 生命機能研究科, 特任研究員(常勤) (30525340)

Project Period (FY) 2014-04-01 – 2017-03-31
Keywords形態形成 / 電気シグナル / 光遺伝学
Outline of Final Research Achievements

In this study, optogenetics techniques were introduced into zebrafish pigment cells. When illuminated by blue light, Channelrhodopsin-2 expressing melanophores were artificially depolarized and showed enhanced cellular motility in vitro. Using this technique, we then artificially altered skin pattern in vivo by switching rearing light conditions. The resulting pattern indicated that a reaction-diffusion system is viable in zebrafish skin pattern formation process.

Free Research Field

発生生物学

URL: 

Published: 2018-03-22  

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