2016 Fiscal Year Final Research Report
Fundamental research for advanced use of polyethylene terephthalate-degrading enzymes
Project/Area Number |
26850053
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Applied microbiology
|
Research Institution | Kyoto University |
Principal Investigator |
Yoshida Shosuke 京都大学, 白眉センター, 特定准教授 (80610766)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Keywords | ポリエチレンテレフタレート / PETase / MHETase / 加水分解酵素 / ゲノム解析 |
Outline of Final Research Achievements |
For the advanced use of two novel enzymes PET hydrolase (PETase) and mono (hydroxyethyl) terephthalate (MHET) hydrolase (MHETase) found from a poly(ethylene terephthalate) (PET)-degrading bacterium, these enzymes have been functionally identified, developed for the abundant soluble protein expression, and functionally improved. As a result, detailed functions of PETase has been identified and PETase mutants with improved thermal stability has been obtained.
|
Free Research Field |
応用微生物学
|