2016 Fiscal Year Final Research Report
Effects of dietary fiber intake on development of Payer's patch in rats
| Project/Area Number |
26850079
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Food science
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| Research Institution | Shizuoka University |
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Principal Investigator |
Hino Shingo 静岡大学, 農学部, 助教 (70547025)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 食物繊維 |
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| Outline of Final Research Achievements |
This study aimed to examine the effects of dietary fiber ingestion on intestinal immune system, development of Peyer's patch in particular. In rat study, ingestion of dietary fiber did not affect the number of Peyer's patch in the small intestine. However, dietary fiber increased the size of Peyer's patch in the lower part of small intestine (ileum). Further, our study revealed that ingestion of dietary fiber up regulated expression level of cytokine such as IL-17 and IFN-g. These results indicated that dietary fiber affects immune system in the small intestine.
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| Free Research Field |
栄養化学
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