Mechanisms of changes in body temperature induced by intake of food components via thermo TRP channels

2016 Fiscal Year Final Research Report

• Project/Area Number: 26850086
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Food science
• Research Institution: The University of Shiga Prefecture
• Principal Investigator: Mori Noriyuki 滋賀県立大学, 人間文化学部, 助教 (90585184)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: TRPチャネル / 体温調節 / 食品成分 / マウス / 熱産生

Outline of Final Research Achievements

In this study, to elucidate the mechanisms of changes in body temperature induced by food intake, we focused on thermo TRP channels that have been indicated to have physiological roles in a perception of temperature and examined changes in body temperatures induced by food components activating these channels with mice. We found that the intake of food components which activate TRPV1, TRPM8, and TRPA1, respectively, changed body temperatures with the activation-temperature-range of each TRP channel, and suggested that these changes in body temperature were mediated by each TRP channel.

Free Research Field

食品科学、体温生理学、栄養化学