2016 Fiscal Year Final Research Report
Relarionship among cationic amino acid transporter, protein metabolism, and energy metabolism in porcine skeletal muscle
Project/Area Number |
26850170
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Animal production science
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Research Institution | National Agriculture and Food Research Organization |
Principal Investigator |
Ishida Aiko 国立研究開発法人農業・食品産業技術総合研究機構, 畜産研究部門 家畜代謝栄養研究領域, 主任研究員 (30414684)
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Project Period (FY) |
2014-04-01 – 2017-03-31
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Keywords | ブタ / 塩基性アミノ酸トランスポーター / タンパク質栄養 / エネルギー不足 |
Outline of Final Research Achievements |
Although The expression of Cat-1 mRNA increased in skeletal muscle of pigs fed low protein diet increased, but the expression of Cat-2 mRNA did not change. The expression of Cat-1 mRNA did not change, but the expression of Cat-2 mRNA increased in skeletal muscle of pigs restricted diet. The results of C2C12 experiment suggest that the deficiency of amino acid directly induce the expression of Cat-1 mRNA. Moreover, the results of C2C12 experiment suggest that the increase of Cat-2 expression by restrictive diet was not induced directly by energy restriction, but by low concentration of IGF-1 of serum.
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Free Research Field |
家畜栄養
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