Relarionship among cationic amino acid transporter, protein metabolism, and energy metabolism in porcine skeletal muscle

2016 Fiscal Year Final Research Report

• Project/Area Number: 26850170
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Animal production science
• Research Institution: National Agriculture and Food Research Organization
• Principal Investigator: Ishida Aiko 国立研究開発法人農業・食品産業技術総合研究機構, 畜産研究部門 家畜代謝栄養研究領域, 主任研究員 (30414684)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: ブタ / 塩基性アミノ酸トランスポーター / タンパク質栄養 / エネルギー不足

Outline of Final Research Achievements

Although The expression of Cat-1 mRNA increased in skeletal muscle of pigs fed low protein diet increased, but the expression of Cat-2 mRNA did not change. The expression of Cat-1 mRNA did not change, but the expression of Cat-2 mRNA increased in skeletal muscle of pigs restricted diet. The results of C2C12 experiment suggest that the deficiency of amino acid directly induce the expression of Cat-1 mRNA. Moreover, the results of C2C12 experiment suggest that the increase of Cat-2 expression by restrictive diet was not induced directly by energy restriction, but by low concentration of IGF-1 of serum.

Free Research Field

家畜栄養