2017 Fiscal Year Final Research Report
Study on prevention of perioperative hypothermia by amino acid in dogs
Project/Area Number |
26850197
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Veterinary medical science
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Research Institution | Gifu University |
Principal Investigator |
SHIBATA Sanae 岐阜大学, 応用生物科学部, 准教授 (20588917)
|
Project Period (FY) |
2014-04-01 – 2018-03-31
|
Keywords | 犬 / アミノ酸輸液 / 周術期低体温 |
Outline of Final Research Achievements |
Amino acid infusion in dogs inhibited insulin secretion reduced the effect which attenuates the decrease in body temperature during anesthesia. Therefore, in healthy dogs, amino acid infusion can attenuates the decrease in body temperature during anesthesia by facilitating insulin secretion. In skeletal muscle and liver derived from dogs infused amino acids, Akt-mTOR pathway was activated. In addition, Akt-mTOR pathway in skeletal muscle can be activated without insulin.
|
Free Research Field |
獣医麻酔学
|