2015 Fiscal Year Final Research Report
Carbon-carbon bond formation reaction by using Pt complex containing non-innocent ligand
| Project/Area Number |
26860006
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical pharmacy
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| Research Institution | Toho University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Keywords | 反応化学 |
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| Outline of Final Research Achievements |
In this study, carbon(sp3)-carbon(sp3) and carbon(sp3)-CN bond formation using a catalytic amount of platinum complex containing redox-active ligands is realized. The process involves a CDC-type bond formation and proceeds efficiently under air atmosphere with Pt(II)-bis(ortho-semibenzoquinonate) complex as a catalyst. Among a variety of solvents tested, dimethyl sulfoxide was found to be the best. However it is suggested that the reaction underwent without Pt-catalyst under mild conditions. Disappointingly the possible involvement of trace amounts of metal complexes in the reaction mixture that were catalyzing our process cannot be completely eliminated.
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| Free Research Field |
反応有機化学
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