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2015 Fiscal Year Final Research Report

Study of Rules and Functions with Aquaporin 0

Research Project

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Project/Area Number 26860149
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field General physiology
Research InstitutionKeio University

Principal Investigator

Nakazawa Yosuke  慶應義塾大学, 薬学部, 助教 (60411708)

Project Period (FY) 2014-04-01 – 2016-03-31
Keywords水晶体 / 水チャネル / 白内障
Outline of Final Research Achievements

(1) The permeation assay of AQP0 was used the stable L-cell line expressing AQP0. As the result, AQP0 can permeate ascorbic acid ex vivo, and also indicate that there is a difference between the import and export of ascorbic acid via AQP0 channel.
(2) The cell adhesion assay of AQP0 was revealed that AQP0 could bind directly to the opposing membrane.

Free Research Field

生物学

URL: 

Published: 2017-05-10  

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