Stress modified nociceptive responses in the anterior cingulate neurons during estrous cycle in female rats

2015 Fiscal Year Final Research Report

• Project/Area Number: 26860382
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Pain science
• Research Institution: Nagasaki University
• Principal Investigator: YAMASHITA Hiromi 長崎大学, 医歯薬学総合研究科(歯学系), 助教 (50706174)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Keywords: 帯状回 / 性周期 / 情動 / 侵害刺激

Outline of Final Research Achievements

The pain is the warning signal which tells danger for a living body, and I have the important role. A relation between a pain and a stress is watched in recent years. But there are a lot of unclear points for participation of a sexual cycle. So vagina sumea of a female rat was extracted, a sexual cycle was specified by Giemsa stain and an experiment was made. For 6 hours, a day a wire netting restriction stress was performed as a continuous stress load. After noxial stimulus used a pinch stimulus and analyzed a reply of the beltlike time of the time of noxial stimulus, it increased in a reply of excitability in estrus.

Free Research Field

感覚生理学