2015 Fiscal Year Final Research Report
Analysis of immune escape mechanism of novel HIV-2 variants isolated from AIDS patients
| Project/Area Number |
26860777
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Infectious disease medicine
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| Research Institution | Okayama University (2015)
National Hospital Organization Nagoya Medical Center (2014) |
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Principal Investigator |
Nemoto Michiko 岡山大学, その他の研究科, 助教 (30625926)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Keywords | HIV-2 / 組換え流行株 / 宿主因子 |
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| Outline of Final Research Achievements |
In vitro replication kinetics of novel HIV-2 circulating recombinant forms in various cell lines as well as in primary cells have been studied. The chemokine receptor CCR5 is used by novel HIV-2 circulating recombinant forms as a coreceptor to enter cells. The findings from this study not only offer academic knowledge of novel HIV-2 circulating recombinant forms, but also help improve treatment for these novel HIV-2 infected patients.
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| Free Research Field |
医歯薬学
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