2015 Fiscal Year Final Research Report
Analysis of the spread of cytomegalovirus in the placenta
| Project/Area Number |
26860857
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Embryonic/Neonatal medicine
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| Research Institution | National Institute of Infectious Diseases |
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Principal Investigator |
Yamada Soichi 国立感染症研究所, ウイルス第一部, 主任研究官 (10514119)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Keywords | 経胎盤感染 |
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| Outline of Final Research Achievements |
Human cytomegalovirus (HCMV) infection to pregnant women causes congenital infection to the fetus through the placenta. The virological analysis in placenta was performed using guinea pig and guinea pig CMV (GPCMV) model. In this study, construction of a guinea pig placental trophoblast cells culture system, and co-culture system of placental cells and macrophages using the chamber system were conducted to analize the virus spread in the placenta. The culture system of trophoblast cells was not established, and the clear image of viral spread was not observed in this study.
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| Free Research Field |
ウイルス学
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