2016 Fiscal Year Final Research Report
The efficancy of YC-1 transarterial chemoembolization besed on hypoxia response
| Project/Area Number |
26860968
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Hirosaki University |
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Principal Investigator |
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| Research Collaborator |
TAKAI Yoshihiro 一般財団法人 脳神経疾患研究所, 南東北BNCT研究センター, センター長
SATOU Mariko 弘前大学, 大学院医学研究科, 助教
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 低酸素 / 肝細胞癌 |
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| Outline of Final Research Achievements |
Previous studies reported that cancer cell get theraputic resistance in hypoxia. Hepatocellular carcinoma has same report.In this study,we investigated the efficancy ofcombination of YC-1 and drug eluting beads.We could not find good conditions of
conbination of these. On the other hand, we investigated other drug.We find that metformin improve theraputic resistance of hepatocellular carcinom in hypoxia.
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| Free Research Field |
放射線科学
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