2015 Fiscal Year Final Research Report
Development of a novel radiotherapy method for pancreatic cancer by using antioxidant and absorbable spacer to protect an intestinal canal.
| Project/Area Number |
26860997
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
|
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| Research Institution | Kobe University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Keywords | 放射線治療 / 放射線防護 / 膵がん |
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| Outline of Final Research Achievements |
Radiotherapy for pancreatic cancer is difficult to deliver curative dose because of risk organs surrounded pancreas. To overcome this problem, we developed a novel radiotherapy method using a novel absorbable spacer. And, we also confirmed the radioprotective effect using Reduced CoQ10. From our experiments, a novel spacer can reduce the radiation damage of intestine, and Reduced CoQ10 can suppress the generation of apoptosis induced by radiation in the intestine. As a result, the survival rate of an experimental animal in this study was improved.
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| Free Research Field |
放射線科学
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