2015 Fiscal Year Final Research Report
MR lymphangiography using gadolinium (GD) -DTPA - nanodiamond particles
| Project/Area Number |
26861019
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Tokai University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Keywords | ナノダイヤモンド / MRI / リンパ管造影 |
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| Outline of Final Research Achievements |
Techniques to visualize the lymphatic system have lagged behind imagings of the cardiovascular system. Our purpose is to use the gadolinium (GD) -diethylenetriaminepentaacetic acid (DTPA) -nanodaiamond (ND) to safely and effectively image the lymphatics on magnetic resonance (MR) lymphangiography. MRI experiments on the GD-DTPA-ND particles indicated their high signal intensity on T1-weighted images. GD-DTPA-ND cell viability test shows the comparable result with existing GD-DTPA. Now, MR lymphangiography using the GD-DTPA-ND in small animal model is currently in progress.
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| Free Research Field |
放射線医学 (血管内治療・画像化治療)
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