Development of diagnostic method of fluorescence during colorectal cancer surgery using 5-aminolevulinic acid and ICG

2016 Fiscal Year Final Research Report

• Project/Area Number: 26861090
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Digestive surgery
• Research Institution: Kagoshima University
• Principal Investigator: BABA KENJI 鹿児島大学, 附属病院, 医員 (30642615)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 大腸癌 / 腹腔鏡手術 / 蛍光診断法

Outline of Final Research Achievements

Recently, laparoscopic surgery for colorectal cancer has been spreading as a standard surgical procedure in addition to laparotomy surgery. The purpose of this study is development of method to identify colorectal cancer mainly using fluorescent endoscopy under laparoscopic surgery. We used commonly available ICG for colorectal cancer surgery, and examined how ICG can be detected in the patient intraperitoneal under the fluorescence laparoscopey . We confirmed that it is possible to evaluate intestinal blood flow after intravenous administration, and it is possible to identify lymph flow and lymph nodes around the tumor by direct injection in the vicinity of the tumor. We reported that laparoscopic colorectal surgery using these methods was safe and new technique in several academic societies.

Free Research Field

消化器外科