2017 Fiscal Year Final Research Report
Development of a novel artificial trachea using autologous chondrocytes and fibroblasts
| Project/Area Number |
26861403
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Fukushima Medical University |
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Principal Investigator |
Nomoto Mika 福島県立医科大学, 医学部, 講師 (50554416)
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Keywords | 再生医療 / 人工気管 / 軟骨細胞 / 線維芽細胞 |
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| Outline of Final Research Achievements |
In our previous study, tracheal regeneration was successfully achieved by using bio-engineered trachea with chondrocytes. Otherwise, delay of epithelization on the inner lumen of bio-engineered trachea was observed. Delay of epithelization may cause some problems including infection or tracheal stenosis.
The purpose of this was to develop a novel hybrid bio-engineered trachea with chondrocyte and fibroblasts, and to verify the effects of the trachea. As a result, cartilaginous regeneration was suppreded.
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| Free Research Field |
医歯薬学
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