2016 Fiscal Year Final Research Report
tinnitus in aging model mice
| Project/Area Number |
26861414
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Otorhinolaryngology
|
|---|
| Research Institution | Keio University |
|---|
Principal Investigator |
Oishi Naoki 慶應義塾大学, 医学部(信濃町), 講師 (10348740)
|
|---|
| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Keywords | 耳鳴 / 加齢 |
|---|
| Outline of Final Research Achievements |
Tinnitus in aging model mice was evaluated by gap detection test (GDT). Tinnitus accompanied by presbycusis was accessed prospectively and individually in CBA/J mice.
The hearing level and GDT were measured periodically from the age of 9 months to 20 months. The hearing level deteriorated according to their age and tinnitus at 24 kHz was detected by GDT at the age of 20 months.
These results are expected to lead to the finding of therapy on tinnitus followed by chronic hearing loss such as aging.
|
| Free Research Field |
耳科学
|
