2016 Fiscal Year Final Research Report
Photoreceptor-specific role of mitochondria
| Project/Area Number |
26861437
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Ophthalmology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
Ueta Takashi 東京大学, 医学部附属病院, 登録研究員 (90631573)
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| Research Collaborator |
ROGGIA Murilo F.
AMANO Shiro
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 網膜変性 / ミトコンドリア異常 / 視細胞 / transcriptional factor A |
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| Outline of Final Research Achievements |
Mouse lacking transcription factor A (TFAM) in photoreceptor cells were created to test the importance of the gene in photoreceptors. Interestingly, The TFAM deficient photoreceptor precursors were able to differentiated into cone and rod photoreceptors, but then followed by cone-rod dystrophy phenotypes.
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| Free Research Field |
網膜硝子体疾患
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