functional, morphological, and molecular biological analysis of macular edema secondary to retinal vein occlusion

2016 Fiscal Year Final Research Report

• Project/Area Number: 26861444
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Ophthalmology
• Research Institution: Nagoya University
• Principal Investigator: Yasuda Shunsuke 名古屋大学, 医学部附属病院, 病院助教 (60718419)
• Research Collaborator: TERASAKI Hiroko 名古屋大学, 大学院医学系研究科眼科学, 教授 (40207478) ; KONDO Mineo 三重大学, 大学院医学系研究科眼科学, 教授 (80303642) ; ITO Yasuki 名古屋大学, 大学院医学系研究科眼科学, 准教授 (10313991) ; KACHI Shu 医療法人豊潤会松浦眼科, 副院長 (30345904) ; ASAMI Tetsu 医療法人湘山会眼科三宅病院, 副院長 (40378005) ; UENO Shinji 名古屋大学, 医学部附属病院, 講師 (80528670) ; IWASE Takeshi 名古屋大学, 医学部附属病院, 講師 (80642339) ; KANEKO Hiroki 名古屋大学, 医学部附属病院, 病院講師 (20647458)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 網膜静脈閉塞症 / 抗VEGF治療

Outline of Final Research Achievements

We reported that the degree of venous tortuosity was significantly correlated with the aqueous vascular endothelial growth factor (VEGF) concentration in eyes with a central retinal vein occlusion (CRVO). We also reported that the implicit times of the flicker electroretinograms (ERG) were significantly shortened one month after an intravitreal injection of ranibizumab (IVR) in eyes with CRVO. The shortening of the implicit times of the flicker ERGs after the IVR indicates an improvement of retinal function after anti-VEGF therapy for CRVO eyes.

Free Research Field

眼科学