2015 Fiscal Year Final Research Report
Functional morphology analysis of an autophagy and Gene therapy on the pancreatic B cell in an inflammation stimulus
| Project/Area Number |
26861530
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Emergency medicine
|
|---|
| Research Institution | Shumei University |
|---|
Principal Investigator |
TERAMAE Hiroki 秀明大学, 人文社会・教育科学系, 准教授 (90599028)
|
|---|
| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Keywords | 膵B細胞 / Autophagy / オートファジー / 炎症 |
|---|
| Outline of Final Research Achievements |
Severe sepsis is easy to combine systemic inflammation by pro inflammatory cytokines production but an effective remedy hasn't been established yet.
In this study, I cultured pancreatic B cell line Min6, provided inflammation stimulus on it and examined how the autophagy effects mRNAs, proteins and morphology in this cell line.
Together these results, I will analyze those of the cells knocked down autophagy derived protein and summarized this monograph.
|
| Free Research Field |
救急医学
|
