Assesment of creation and leading of remineralization of artificial caries affected dentin using Fluoride and Calcium containing materials

2016 Fiscal Year Final Research Report

• Project/Area Number: 26861590
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Conservative dentistry
• Research Institution: Tokyo Medical and Dental University
• Principal Investigator: INOUE GO 東京医科歯科大学, 大学院医歯学総合研究科, 助教 (40431928)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: FCP-COMPLEX / caries affected dentin / remineralization / fluoride

Outline of Final Research Achievements

The application of Fluoride, Calcium and Phosphate containing solution, so-called FCP-COMPLEX or Sodium Fluoride solution had good effects on the dentin-adhesive interface, after making the artificial caries affected dentin model with bovine and human tooth. Especially FCP-COMPLEX solution could penetrate into deeper area of the artificial caries affetced dentin than normal dentin, and could resist the secondary acid attack at the surface. These results were observed by SEM. Also a creation of CaF on the superfacial layer could be detected by using XAFS, but it was in conjecture that fluoroapatite could be created in deeper area.

Free Research Field

医歯薬学