2015 Fiscal Year Final Research Report
The analysis of dendritic cells in rat denatl pulp
| Project/Area Number |
26861592
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Conservative dentistry
|
|---|
| Research Institution | Tokyo Medical and Dental University |
|---|
Principal Investigator |
Aramaki Oto 東京医科歯科大学, 歯学部附属病院, 医員 (60634615)
|
|---|
| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Keywords | 歯髄 / 樹状細胞 / う蝕 |
|---|
| Outline of Final Research Achievements |
We confirmed that there existed the MHC classII and CD11c positive dendritic cells in rat normal dental pulp by immunohistochemistry. And we also showed the CD103-positive dendritic cells in rat normal dental pulp. It is suggested that adaptive immunity (mainly dendritic cells) may play an important role in dental pulp. We further showed that there are Iba1 positive cells which have ramifications in the front of human dental pulp by three-dimensional analysis. From our findings, there are many macrophages in the front of dental pulp which may induce adaptive immunity.
|
| Free Research Field |
う蝕制御学
|
