Establishment of the isolation method of odontoblasts and clarification of the mechanism of the dentinal tuble formation.

2015 Fiscal Year Final Research Report

• Project/Area Number: 26861600
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Conservative dentistry
• Research Institution: Nagasaki University
• Principal Investigator: NAKAJIMA Kazunori 長崎大学, 医歯薬学総合研究科(歯学系), 助教 (40707246)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Keywords: 象牙芽細胞 / Tie2

Outline of Final Research Achievements

Dentin is located inside of enamal and added by foreign stimulation throughout our life by odonoblastst. Because odontoblasts have not been isolated so far, their biological features were not known well. The aim of this study was to isolate odontoblasts from pulp tissues by targeting the specific molecule expressed by odontoblasts. As a results, odontoblasts were isolated , however, it was suggested that their long-time culture required additional certain factors to maintain their biological features. This findings may contribute ti the development of the researchs of odontoblasts cell biology.

Free Research Field

歯科補綴学