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2015 Fiscal Year Final Research Report

Establishment of the remineralization therapy that targeted root caries- application of Peptide P11-4

Research Project

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Project/Area Number 26861608
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Conservative dentistry
Research InstitutionNihon University

Principal Investigator

TAKIMOTO Masayuki  日本大学, 歯学部, 専修医 (90723239)

Project Period (FY) 2014-04-01 – 2016-03-31
Keywords根面齲蝕 / 脱灰抑制 / 再石灰化 / ペプチド / 光干渉断層画像法 / 超音波測定装置
Outline of Final Research Achievements

This study evaluates the effect of self-assembling peptide P11-4 on bovine
dentin remineralization by measuring changes in ultrasonic propagation velocity and using opticalcoherence tomography. Sonic velocity was found to decrease with time for specimens stored in the demineralizing solution. On the other hand, increases in sonic velocity were found for specimens treated with P11-4 . By measuring the ultrasonic propagation velocity, it can be concluded that P11-4 application has an ability to promote bovine dentin remineralization.

Free Research Field

保存修復学

URL: 

Published: 2017-05-10  

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