2016 Fiscal Year Final Research Report
Restoring occlusion in rats with missing molar teeth stabilizes their emotions
| Project/Area Number |
26861666
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Prosthodontics/ Dental materials science and
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| Research Institution | Osaka Dental University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | ホールボード試験 / 情動行動 / 不安 / 咬合障害 |
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| Outline of Final Research Achievements |
To clarify the effects of altered occlusion on psychological stress, I observed emotional behavior changes in rats that experienced occlusal interference. Nine male Sprague-Dawley rats were randomly assigned to a control group, an interference group, or a temporary interference group, each with 3 rats. The interference group rats were given aluminum laminates on the occlusal surface of their teeth, the temporary interference group rats were given temporary laminates for 30 minutes, and the control group rats underwent a sham operation. I recorded the frequency and duration of head-dipping, total activity time, and movement distance, all of which decrease when rats are depressed.
The rats with disrupted occlusion exhibited lower head-dipping frequencies than the control group and temporary interference group rats. This suggests that occlusal interference causes psychological stress in rats.
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| Free Research Field |
医歯薬学系
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