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2015 Fiscal Year Final Research Report

Development of cancer immunotherapy using nanogel

Research Project

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Project/Area Number 26861741
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Surgical dentistry
Research InstitutionKyoto Prefectural University of Medicine

Principal Investigator

ADACHI TETSUYA  京都府立医科大学, 医学部附属病院, 専攻医 (10613573)

Project Period (FY) 2014-04-01 – 2016-03-31
Keywordsナノゲル
Outline of Final Research Achievements

RNAi(RNA interference) enables potent and specific gene silencing, potentially offering useful means for treatment of cancers. However, safe and efficient drug delivery systems (DDS) that are appropriate for tumor microenvironment delivery of siRNA have rarely been established, hindering clinical application of RNAi technology to cancer therapy. We develop cholesterol-bearing cycloamylose with spermine group (CH-CA-Spe) , and shown its validity as a novel DDS for siRNA.

Free Research Field

バイオマテリアル

URL: 

Published: 2017-05-10  

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