2015 Fiscal Year Final Research Report
Explication of the mechanism and new therapy in refractory chronic orofacial pain
| Project/Area Number |
26861756
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Surgical dentistry
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| Research Institution | Tsurumi University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Keywords | 口腔顔面痛 / エンドセリン / 神経障害性疼痛 |
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| Outline of Final Research Achievements |
We investigated the effect of endothelin in orofacial pain. In the present study, the injection of endothelin-1(ET-1) at whisker pad prolonged the duration of the pain-related behavior. This result suggests that endothelin has some sort of effect for orofacial pain. Subsequently, we prepared the neuropathic pain model rat(transection・ligation).
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| Free Research Field |
神経障害性疼痛
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